Characterization of the multimeric structure of poly(A)-binding protein on a poly(A) tail

Eukaryotic mature mRNAs possess a poly adenylate tail (poly(A)), to which multiple molecules of poly(A)-binding protein C1 (PABPC1) bind. PABPC1 regulates translation and mRNA metabolism by binding to regulatory proteins. To understand functional mechanism of the regulatory proteins, it is necessary...

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Vydáno v:Sci Rep
Hlavní autoři: Sawazaki, Ryoichi, Imai, Shunsuke, Yokogawa, Mariko, Hosoda, Nao, Hoshino, Shin-ichi, Mio, Muneyo, Mio, Kazuhiro, Shimada, Ichio, Osawa, Masanori
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780489/
https://ncbi.nlm.nih.gov/pubmed/29362417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19659-6
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