Biological role of the two overlapping poly(A)-binding protein interacting motifs 2 (PAM2) of eukaryotic releasing factor eRF3 in mRNA decay

Eukaryotic releasing factor GSPT/eRF3 mediates translation termination-coupled mRNA decay via interaction with a cytosolic poly(A)-binding protein (PABPC1). A region of eRF3 containing two overlapping PAM2 (PABPC1-interacting motif 2) motifs is assumed to bind to the PABC domain of PABPC1, on the po...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Osawa, Masanori, Hosoda, Nao, Nakanishi, Tamiji, Uchida, Naoyuki, Kimura, Tomomi, Imai, Shunsuke, Machiyama, Asako, Katada, Toshiaki, Hoshino, Shin-ichi, Shimada, Ichio
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479387/
https://ncbi.nlm.nih.gov/pubmed/23019593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.035311.112
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker