Fission yeast Ccq1 is a modulator of telomerase activity

Shelterin, the telomeric protein complex, plays a crucial role in telomere homeostasis. In fission yeast, telomerase is recruited to chromosome ends by the shelterin component Tpz1 and its binding partner Ccq1, where telomerase binds to the 3′ overhang to add telomeric repeats. Recruitment is initia...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Armstrong, Christine A, Moiseeva, Vera, Collopy, Laura C, Pearson, Siân R, Ullah, Tomalika R, Xi, Shidong T, Martin, Jennifer, Subramaniam, Shaan, Marelli, Sara, Amelina, Hanna, Tomita, Kazunori
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Genome Integrity, Repair and Replication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778466/
https://ncbi.nlm.nih.gov/pubmed/29216371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1223
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