Fission yeast Ccq1 is a modulator of telomerase activity

Shelterin, the telomeric protein complex, plays a crucial role in telomere homeostasis. In fission yeast, telomerase is recruited to chromosome ends by the shelterin component Tpz1 and its binding partner Ccq1, where telomerase binds to the 3′ overhang to add telomeric repeats. Recruitment is initia...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Armstrong, Christine A, Moiseeva, Vera, Collopy, Laura C, Pearson, Siân R, Ullah, Tomalika R, Xi, Shidong T, Martin, Jennifer, Subramaniam, Shaan, Marelli, Sara, Amelina, Hanna, Tomita, Kazunori
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778466/
https://ncbi.nlm.nih.gov/pubmed/29216371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1223
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