Fission yeast Ccq1 is a modulator of telomerase activity

Shelterin, the telomeric protein complex, plays a crucial role in telomere homeostasis. In fission yeast, telomerase is recruited to chromosome ends by the shelterin component Tpz1 and its binding partner Ccq1, where telomerase binds to the 3′ overhang to add telomeric repeats. Recruitment is initia...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Armstrong, Christine A, Moiseeva, Vera, Collopy, Laura C, Pearson, Siân R, Ullah, Tomalika R, Xi, Shidong T, Martin, Jennifer, Subramaniam, Shaan, Marelli, Sara, Amelina, Hanna, Tomita, Kazunori
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Genome Integrity, Repair and Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778466/
https://ncbi.nlm.nih.gov/pubmed/29216371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1223
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