Fission yeast Ccq1 is a modulator of telomerase activity

Shelterin, the telomeric protein complex, plays a crucial role in telomere homeostasis. In fission yeast, telomerase is recruited to chromosome ends by the shelterin component Tpz1 and its binding partner Ccq1, where telomerase binds to the 3′ overhang to add telomeric repeats. Recruitment is initia...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Armstrong, Christine A, Moiseeva, Vera, Collopy, Laura C, Pearson, Siân R, Ullah, Tomalika R, Xi, Shidong T, Martin, Jennifer, Subramaniam, Shaan, Marelli, Sara, Amelina, Hanna, Tomita, Kazunori
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
Assuntos:
Genome Integrity, Repair and Replication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778466/
https://ncbi.nlm.nih.gov/pubmed/29216371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1223
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