In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis

Mycobacterium tuberculosis continues to cause devastating levels of mortality due to tuberculosis (TB). The failure to control TB stems from an incomplete understanding of the highly specialized strategies that M. tuberculosis utilizes to modulate host immunity and thereby persist in host lungs. Her...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Gautam, Uma S., Foreman, Taylor W., Bucsan, Allison N., Veatch, Ashley V., Alvarez, Xavier, Adekambi, Toidi, Golden, Nadia A., Gentry, Kaylee M., Doyle-Meyers, Lara A., Russell-Lodrigue, Kasi E., Didier, Peter J., Blanchard, James L., Kousoulas, K. Gus, Lackner, Andrew A., Kalman, Daniel, Rengarajan, Jyothi, Khader, Shabaana A., Kaushal, Deepak, Mehra, Smriti
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2018
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776797/
https://ncbi.nlm.nih.gov/pubmed/29255022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711373114
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