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Nonpathologic Infection of Macaques by an Attenuated Mycobacterial Vaccine Is Not Reactivated in the Setting of HIV Co-Infection

Failure to replace Bacille Calmette-Guerin vaccines with efficacious anti-tuberculosis (TB) vaccines have prompted outside-the-box thinking, including pulmonary vaccination to elicit local immunity. Inhalational MtbΔsigH, a stress-response–attenuated strain, protected against lethal TB in macaques....

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Foreman, Taylor W., Veatch, Ashley V., LoBato, Denae N., Didier, Peter J., Doyle-Meyers, Lara A., Russell-Lodrigue, Kasi E., Lackner, Andrew A., Kousoulas, Konstantin G., Khader, Shabaana A., Kaushal, Deepak, Mehra, Smriti
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718104/
https://ncbi.nlm.nih.gov/pubmed/28935575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.08.014
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