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Design, synthesis, and biological evaluation of 6-methoxy-2-arylquinolines as potential P-glycoprotein inhibitors
OBJECTIVE(S): In the present study, a new series of 6-methoxy-2-arylquinoline analogues was designed and synthesized as P-glycoprotein (P-gp) inhibitors using quinine and flavones as the lead compounds. MATERIALS AND METHODS: The cytotoxic activity of the synthesized compounds was evaluated against...
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| Veröffentlicht in: | Iran J Basic Med Sci |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Mashhad University of Medical Sciences
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5776443/ https://ncbi.nlm.nih.gov/pubmed/29372031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2017.21892.5616 |
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