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Design, synthesis, and biological evaluation of novel 5,6,7-trimethoxy quinolines as potential anticancer agents and tubulin polymerization inhibitors

OBJECTIVE(S): Microtubules have key roles in essential cellular processes such as mitosis, cell motion, and intracellular organelle transport. Increasing interest has been given to tubulin binding compounds after the introduction of taxanes into clinical oncology. The object of this study was synthe...

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Dettagli Bibliografici
Pubblicato in:Iran J Basic Med Sci
Autori principali: Mirzaei, Salimeh, Eisvand, Farhad, Hadizadeh, Farzin, Mosaffa, Fatemeh, Ghodsi, Razieh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mashhad University of Medical Sciences 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811808/
https://ncbi.nlm.nih.gov/pubmed/33489025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.43303.10168
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