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Design, synthesis, and biological evaluation of novel 5,6,7-trimethoxy quinolines as potential anticancer agents and tubulin polymerization inhibitors
OBJECTIVE(S): Microtubules have key roles in essential cellular processes such as mitosis, cell motion, and intracellular organelle transport. Increasing interest has been given to tubulin binding compounds after the introduction of taxanes into clinical oncology. The object of this study was synthe...
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| Опубликовано в: : | Iran J Basic Med Sci |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Mashhad University of Medical Sciences
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7811808/ https://ncbi.nlm.nih.gov/pubmed/33489025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.43303.10168 |
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