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Design, synthesis, and biological evaluation of novel 5,6,7-trimethoxy quinolines as potential anticancer agents and tubulin polymerization inhibitors

OBJECTIVE(S): Microtubules have key roles in essential cellular processes such as mitosis, cell motion, and intracellular organelle transport. Increasing interest has been given to tubulin binding compounds after the introduction of taxanes into clinical oncology. The object of this study was synthe...

詳細記述

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書誌詳細
出版年:Iran J Basic Med Sci
主要な著者: Mirzaei, Salimeh, Eisvand, Farhad, Hadizadeh, Farzin, Mosaffa, Fatemeh, Ghodsi, Razieh
フォーマット: Artigo
言語:Inglês
出版事項: Mashhad University of Medical Sciences 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811808/
https://ncbi.nlm.nih.gov/pubmed/33489025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.43303.10168
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