Discovery of Novel 4-Arylisochromenes as Anticancer Agents Inhibiting Tubulin Polymerization

[Image: see text] XJP-L (8), a derivative of the natural product (±)-7,8-dihydroxy-3-methylisochroman-4-one isolated from the peel of Musa sapien tum L., was found to exhibit weak inhibitory activity of tubulin polymerization (IC(50) = 10.6 μM) in our previous studies. Thus, a series of 4-arylisochr...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:ACS Med Chem Lett
Main Authors: Li, Wenlong, Shuai, Wen, Xu, Feijie, Sun, Honghao, Xu, Shengtao, Yao, Hong, Liu, Jie, Yao, Hequan, Zhu, Zheying, Xu, Jinyi
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2018
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187416/
https://ncbi.nlm.nih.gov/pubmed/30344902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00217
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki