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The Design and Development of Potent Small Molecules as Anticancer Agents Targeting EGFR TK and Tubulin Polymerization

Some novel anthranilate diamides derivatives 4a–e, 6a–c and 9a–d were designed and synthesized to be evaluated for their in vitro anticancer activity. Structures of all newly synthesized compounds were confirmed by infra-red (IR), high-resolution mass (HR-MS) spectra, (1)H nuclear magnetic resonance...

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Pubblicato in:Int J Mol Sci
Autori principali: Ihmaid, Saleh, Ahmed, Hany E. A., Zayed, Mohamed F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855630/
https://ncbi.nlm.nih.gov/pubmed/29385728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19020408
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