Synthesis and biological evaluation of oxazinonaphthalene-3-one derivatives as potential anticancer agents and tubulin inhibitors

OBJECTIVE(S): In the present study, a new series of oxazinonaphthalene-3-one analogs was designed and synthesized as novel tubulin inhibitors. MATERIALS AND METHODS: The cytotoxic activity of the synthesized compounds was evaluated against four human cancer cell lines including A2780 (human ovarian...

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Bibliografiska uppgifter
I publikationen:Iran J Basic Med Sci
Huvudupphovsmän: Mirzaei, Salimeh, Qayumov, Maqsudjon, Gangi, Fahimeh, Behravan, Javad, Ghodsi, Razieh
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mashhad University of Medical Sciences 2020
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671423/
https://ncbi.nlm.nih.gov/pubmed/33235695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.40845.9648
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