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Thermodynamic Coupling Function Analysis of Allosteric Mechanisms in the Human Dopamine Transporter
Allostery plays a crucial role in the mechanism of neurotransmitter-sodium symporters, such as the human dopamine transporter. To investigate the molecular mechanism that couples the transport-associated inward release of the Na(+) ion from the Na2 site to intracellular gating, we applied a combinat...
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| Publicado en: | Biophys J |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Biophysical Society
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5773750/ https://ncbi.nlm.nih.gov/pubmed/29153319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.10.030 |
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