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How structural elements evolving from bacterial to human SLC6 transporters enabled new functional properties
BACKGROUND: Much of the structure-based mechanistic understandings of the function of SLC6A neurotransmitter transporters emerged from the study of their bacterial LeuT-fold homologs. It has become evident, however, that structural differences such as the long N- and C-termini of the eukaryotic neur...
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| Udgivet i: | BMC Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5852957/ https://ncbi.nlm.nih.gov/pubmed/29540172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-018-0495-6 |
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