Chargement en cours...

The allosteric mechanism of substrate-specific transport in SLC6 is mediated by a volumetric sensor

Neurotransmitter:sodium symporters (NSSs) in the SLC6 family terminate neurotransmission by coupling the thermodynamically favorable transport of ions to the thermodynamically unfavorable transport of neurotransmitter back into presynaptic neurons. Results from many structural, functional, and compu...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: LeVine, Michael V., Terry, Daniel S., Khelashvili, George, Siegel, Zarek S., Quick, Matthias, Javitch, Jonathan A., Blanchard, Scott C., Weinstein, Harel
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689989/
https://ncbi.nlm.nih.gov/pubmed/31324743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903020116
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!