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The allosteric mechanism of substrate-specific transport in SLC6 is mediated by a volumetric sensor
Neurotransmitter:sodium symporters (NSSs) in the SLC6 family terminate neurotransmission by coupling the thermodynamically favorable transport of ions to the thermodynamically unfavorable transport of neurotransmitter back into presynaptic neurons. Results from many structural, functional, and compu...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6689989/ https://ncbi.nlm.nih.gov/pubmed/31324743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903020116 |
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