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In vivo Pig-a and micronucleus study of the prototypical aneugen vinblastine sulfate

The Pig-a assay is being used in regulatory studies to evaluate the potential of agents to induce somatic cell gene mutations and an OECD test guideline is under development. A working group involved with establishing the guideline recently noted that representative aneugenic agents had not been eva...

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Detalhes bibliográficos
Publicado no:Environ Mol Mutagen
Main Authors: Avlasevich, Svetlana L., Labash, Carson, Torous, Dorothea K., Bemis, Jeffrey C., MacGregor, James T., Dertinger, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773054/
https://ncbi.nlm.nih.gov/pubmed/28833575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22122
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