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Comparison of male versus female responses in the Pig-a mutation assay
Validation of the Pig-a gene mutation assay has been based mainly on studies in male rodents. To determine if the mutagen-induced responses of the X-linked Pig-a gene differ in females compared to males, 7- or 14-week old male and female Sprague Dawley rats were exposed to N-ethyl-N-nitrosourea (ENU...
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| Publicado no: | Mutagenesis |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4422866/ https://ncbi.nlm.nih.gov/pubmed/25833915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/geu055 |
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