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Induction of Pig-a mutant erythrocytes in male and female rats exposed to 1,3-propane sultone, ethyl carbamate, or thiotepa
Validation of the Pig-a gene mutation assay has been based mainly on studies in male rodents. To determine if the mutagen-induced responses of the X-linked Pig-a gene differ in females compared to males, groups of five male and female Sprague Dawley rats were exposed to the mutagens 1,3-propane sult...
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| Publicado no: | Mutat Res Genet Toxicol Environ Mutagen |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4395863/ https://ncbi.nlm.nih.gov/pubmed/25868128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2015.03.011 |
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