Dextran sulfate sodium mouse model of inflammatory bowel disease evaluated for systemic genotoxicity via blood micronucleus and Pig-a gene mutation assays

Inflammatory bowel disease (IBD) is an important risk factor for gastrointestinal cancers. Inflammation and other carcinogenesis-related effects at distal, tissue-specific sites require further study. In order to better understand if systemic genotoxicity is associated with IBD, we exposed mice to d...

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Publié dans:Mutagenesis
Auteurs principaux: Kirby, Christopher, Baig, Ayesha, Avlasevich, Svetlana L, Torous, Dorothea K, Tian, Shuchang, Singh, Priyanka, Bemis, Jeffrey C, Saubermann, Lawrence J, Dertinger, Stephen D
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
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Original Manuscript
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373322/
https://ncbi.nlm.nih.gov/pubmed/32050029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/geaa006
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