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In vitro micronucleus assay scored by flow cytometry provides a comprehensive evaluation of cytogenetic damage and cytotoxicity

This laboratory has previously reported on the development of a flow cytometry-based method for scoring in vitro micronuclei in mouse lymphoma (L5178Y) cells [Avlasevich et al., Environ. Molec. Mutagen. 47 (2006) 56-66]. With this method, necrotic and mid/late stage apoptotic cells are labeled with...

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Autori principali: Bryce, Steven M., Bemis, Jeffrey C., Avlasevich, Svetlana L., Dertinger, Stephen D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950716/
https://ncbi.nlm.nih.gov/pubmed/17434794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2007.03.002
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