Pig-a Mutation: Kinetics in Rat Erythrocytes Following Exposure to Five Prototypical Mutagens

An in vivo mutation assay has been developed based on flow cytometric enumeration of glycosylphosphatidylinositol (GPI) anchor–deficient rat erythrocytes. With this method, blood is incubated with anti-CD59-PE and SYTO 13 dye, and flow cytometry is used to score the frequency of CD59-negative erythr...

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Detalhes bibliográficos
Main Authors: Phonethepswath, Souk, Franklin, Dean, Torous, Dorothea K., Bryce, Steven M., Bemis, Jeffrey C., Raja, Sarojini, Avlasevich, Svetlana, Weller, Pamela, Hyrien, Ollivier, Palis, James, MacGregor, James T., Dertinger, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Genetic Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902916/
https://ncbi.nlm.nih.gov/pubmed/19965957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp289
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