Pig-a Mutation: Kinetics in Rat Erythrocytes Following Exposure to Five Prototypical Mutagens

An in vivo mutation assay has been developed based on flow cytometric enumeration of glycosylphosphatidylinositol (GPI) anchor–deficient rat erythrocytes. With this method, blood is incubated with anti-CD59-PE and SYTO 13 dye, and flow cytometry is used to score the frequency of CD59-negative erythr...

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Autori principali: Phonethepswath, Souk, Franklin, Dean, Torous, Dorothea K., Bryce, Steven M., Bemis, Jeffrey C., Raja, Sarojini, Avlasevich, Svetlana, Weller, Pamela, Hyrien, Ollivier, Palis, James, MacGregor, James T., Dertinger, Stephen D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
Soggetti:
Genetic Toxicology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902916/
https://ncbi.nlm.nih.gov/pubmed/19965957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp289
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