A Novel Neuroprotective Mechanism for Lithium That Prevents Association of the p75(NTR)-Sortilin Receptor Complex and Attenuates proNGF-Induced Neuronal Death In Vitro and In Vivo

Neurotrophins play critical roles in the survival, maintenance and death of neurons. In particular, proneurotrophins have been shown to mediate cell death following brain injury induced by status epilepticus (SE) in rats. Previous studies have shown that pilocarpine-induced seizures lead to increase...

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Detalles Bibliográficos
Publicado en:eNeuro
Main Authors: Greenwood, Shayri G., Montroull, Laura, Volosin, Marta, Scharfman, Helen E., Teng, Kenneth K., Light, Matthew, Torkin, Risa, Maxfield, Fredrick, Hempstead, Barbara L., Friedman, Wilma J.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2018
Assuntos:
New Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771681/
https://ncbi.nlm.nih.gov/pubmed/29349290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0257-17.2017
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