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proNGF, sortilin, and p75(NTR): potential mediators of injury-induced apoptosis in the mouse dorsal root ganglion
The nerve growth factor precursor (proNGF) may function as a death-inducing ligand that mediates its apoptotic effects via p75(NTR). ProNGF-induced apoptosis is postulated to be dependent upon membrane expression of the sortilin receptor, which interacts with p75(NTR) to promote a high affinity-bind...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2156563/ https://ncbi.nlm.nih.gov/pubmed/17964555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.09.051 |
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