A Novel Neuroprotective Mechanism for Lithium That Prevents Association of the p75(NTR)-Sortilin Receptor Complex and Attenuates proNGF-Induced Neuronal Death In Vitro and In Vivo

Neurotrophins play critical roles in the survival, maintenance and death of neurons. In particular, proneurotrophins have been shown to mediate cell death following brain injury induced by status epilepticus (SE) in rats. Previous studies have shown that pilocarpine-induced seizures lead to increase...

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Udgivet i:eNeuro
Main Authors: Greenwood, Shayri G., Montroull, Laura, Volosin, Marta, Scharfman, Helen E., Teng, Kenneth K., Light, Matthew, Torkin, Risa, Maxfield, Fredrick, Hempstead, Barbara L., Friedman, Wilma J.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2018
Fag:
New Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771681/
https://ncbi.nlm.nih.gov/pubmed/29349290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0257-17.2017
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