A metabolic function of FGFR3-TACC3 gene fusions in cancer

Chromosomal translocations that generate in-frame oncogenic gene fusions are powerful examples of success of targeted cancer therapies(1–3). We discovered FGFR3-TACC3 (F3-T3) gene fusions in 3% of human glioblastoma(4). Subsequent studies reported similar frequencies of F3-T3 in many other cancers,...

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書誌詳細
出版年:Nature
主要な著者: Frattini, Véronique, Pagnotta, Stefano M., Tala, Fan, Jerry J., Russo, Marco V., Lee, Sang Bae, Garofano, Luciano, Zhang, Jing, Shi, Peiguo, Lewis, Genevieve, Sanson, Heloise, Frederick, Vanessa, Castano, Angelica M., Cerulo, Luigi, Rolland, Delphine C. M., Mall, Raghvendra, Mokhtari, Karima, Elenitoba-Johnson, Kojo S.J., Sanson, Marc, Huang, Xi, Ceccarelli, Michele, Lasorella, Anna, Iavarone, Antonio
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771419/
https://ncbi.nlm.nih.gov/pubmed/29323298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25171
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