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A metabolic function of FGFR3-TACC3 gene fusions in cancer
Chromosomal translocations that generate in-frame oncogenic gene fusions are powerful examples of success of targeted cancer therapies(1–3). We discovered FGFR3-TACC3 (F3-T3) gene fusions in 3% of human glioblastoma(4). Subsequent studies reported similar frequencies of F3-T3 in many other cancers,...
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Publicado no: | Nature |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5771419/ https://ncbi.nlm.nih.gov/pubmed/29323298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25171 |
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