Glucocorticoids Antagonize RUNX2 During Osteoblast Differentiation in Cultures of ST2 Pluripotent Mesenchymal Cells

The efficacy of glucocorticoids (GCs) in treating a wide range of autoimmune and inflammatory conditions is blemished by severe side effects, including osteoporosis. The chief mechanism leading to GC-induced osteoporosis is inhibition of bone formation, but the role of RUNX2, a master regulator of o...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Cell Biochem
Päätekijät: Koromila, Theodora, Baniwal, Sanjeev K., Song, Yae S., Martin, Anthony, Xiong, Jian, Frenkel, Baruch
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771406/
https://ncbi.nlm.nih.gov/pubmed/23943595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24646
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