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PROGRESSIVE RECRUITMENT OF RUNX2 TO GENOMIC TARGETS DESPITE DECREASING EXPRESSION DURING OSTEOBLAST DIFFERENTIATION

The mRNAs encoding Runx2, a master osteoblast transcription factor, and its target gene Osteocalcin (OC), are commonly used as markers of osteoblast differentiation. We found that while OC mRNA levels do indeed increase during development of the osteoblast phenotype in MC3T3-E1 cultures, Runx2 mRNA...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pregizer, Steven, Baniwal, Sanjeev K., Yan, Xiting, Borok, Zea, Frenkel, Baruch
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2591066/
https://ncbi.nlm.nih.gov/pubmed/18821584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21900
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