PROGRESSIVE RECRUITMENT OF RUNX2 TO GENOMIC TARGETS DESPITE DECREASING EXPRESSION DURING OSTEOBLAST DIFFERENTIATION

The mRNAs encoding Runx2, a master osteoblast transcription factor, and its target gene Osteocalcin (OC), are commonly used as markers of osteoblast differentiation. We found that while OC mRNA levels do indeed increase during development of the osteoblast phenotype in MC3T3-E1 cultures, Runx2 mRNA...

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Main Authors: Pregizer, Steven, Baniwal, Sanjeev K., Yan, Xiting, Borok, Zea, Frenkel, Baruch
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2591066/
https://ncbi.nlm.nih.gov/pubmed/18821584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21900
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