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Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity

Wiskott-Aldrich syndrome (WAS) is an immune pathology associated with mutations in WAS protein (WASp) or in WASp interacting protein (WIP). Together with the small GTPase Cdc42 and other effectors, these proteins participate in the remodelling of the actin network downstream of BCR engagement. Here...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Burbage, Marianne, Gasparrini, Francesca, Aggarwal, Shweta, Gaya, Mauro, Arnold, Johan, Nair, Usha, Way, Michael, Bruckbauer, Andreas, Batista, Facundo D
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770159/
https://ncbi.nlm.nih.gov/pubmed/29337666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26556
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