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The Lack of WIP Binding to Actin Results in Impaired B Cell Migration and Altered Humoral Immune Responses
Wiskott-Aldrich syndrome protein (WASp) is a main cytoskeletal regulator in B cells. WASp-interacting protein (WIP) binds to and stabilizes WASp but also interacts with actin. Using mice with a mutated actin binding domain of WIP (WIPΔABD), we here investigated the role of WIP binding to actin durin...
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| Publicat a: | Cell Rep |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cell Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6077251/ https://ncbi.nlm.nih.gov/pubmed/30021160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.06.051 |
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