Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth

Detailed studies of the broadly neutralizing antibodies (bNAbs) that underlie the best available examples of the humoral immune response to HIV are providing important information for the development of therapies and prophylaxis for HIV-1 infection. Here, we report a CD4-binding site (CD4bs) antibod...

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Bibliografiset tiedot
Julkaisussa:Immunity
Päätekijät: Huang, Jinghe, Kang, Byong H., Ishida, Elise, Zhou, Tongqing, Griesman, Trevor, Sheng, Zizhang, Wu, Fan, Doria-Rose, Nicole A., Zhang, Baoshan, McKee, Krisha, O’Dell, Sijy, Chuang, Gwo-Yu, Druz, Aliaksandr, Georgiev, Ivelin S., Schramm, Chaim A., Zheng, Anqi, Joyce, M. Gordon, Asokan, Mangaiarkarasi, Ransier, Amy, Darko, Sam, Migueles, Stephen A., Bailer, Robert T., Louder, Mark K., Alam, S. Munir, Parks, Robert, Kelsoe, Garnett, Von Holle, Tarra, Haynes, Barton F., Douek, Daniel C., Hirsch, Vanessa, Seaman, Michael S., Shapiro, Lawrence, Mascola, John R., Kwong, Peter D., Connors, Mark
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770152/
https://ncbi.nlm.nih.gov/pubmed/27851912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.10.027
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