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Nup98 regulation of histone methylation promotes normal gene expression and may drive leukemogenesis

Nuclear pore proteins (Nups) interact with chromosomes to regulate gene expression and chromatin structure. A new study by Franks and colleagues (pp. 2222–2234) provides new mechanistic insight into the molecular basis by which Nup98 promotes gene activation in normal hematopoietic cells and how tha...

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Detaylı Bibliyografya
Yayımlandı:Genes Dev
Asıl Yazarlar: Sump, Bethany, Brickner, Jason H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769765/
https://ncbi.nlm.nih.gov/pubmed/29284709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.310359.117
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