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Nup98 regulation of histone methylation promotes normal gene expression and may drive leukemogenesis

Nuclear pore proteins (Nups) interact with chromosomes to regulate gene expression and chromatin structure. A new study by Franks and colleagues (pp. 2222–2234) provides new mechanistic insight into the molecular basis by which Nup98 promotes gene activation in normal hematopoietic cells and how tha...

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Detalles Bibliográficos
Publicado en:Genes Dev
Main Authors: Sump, Bethany, Brickner, Jason H.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769765/
https://ncbi.nlm.nih.gov/pubmed/29284709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.310359.117
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