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Nup98 regulation of histone methylation promotes normal gene expression and may drive leukemogenesis
Nuclear pore proteins (Nups) interact with chromosomes to regulate gene expression and chromatin structure. A new study by Franks and colleagues (pp. 2222–2234) provides new mechanistic insight into the molecular basis by which Nup98 promotes gene activation in normal hematopoietic cells and how tha...
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| Pubblicato in: | Genes Dev |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5769765/ https://ncbi.nlm.nih.gov/pubmed/29284709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.310359.117 |
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