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Accurate detection of chemical modifications in RNA by mutational profiling (MaP) with ShapeMapper 2

Mutational profiling (MaP) enables detection of sites of chemical modification in RNA as sequence changes during reverse transcription (RT), subsequently read out by massively parallel sequencing. We introduce ShapeMapper 2, which integrates careful handling of all classes of adduct-induced sequence...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:RNA
Prif Awduron: Busan, Steven, Weeks, Kevin M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769742/
https://ncbi.nlm.nih.gov/pubmed/29114018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.061945.117
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