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Accurate detection of chemical modifications in RNA by mutational profiling (MaP) with ShapeMapper 2

Mutational profiling (MaP) enables detection of sites of chemical modification in RNA as sequence changes during reverse transcription (RT), subsequently read out by massively parallel sequencing. We introduce ShapeMapper 2, which integrates careful handling of all classes of adduct-induced sequence...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:RNA
Egile Nagusiak: Busan, Steven, Weeks, Kevin M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769742/
https://ncbi.nlm.nih.gov/pubmed/29114018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.061945.117
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