Identification of MALT1 as both a prognostic factor and a potential therapeutic target of regorafenib in cholangiocarcinoma patients

Intrahepatic cholangiocarcinoma (CCA) is an aggressive cancer that lacks an effective targeted therapy. Here, we assessed the therapeutic efficacy of regorafenib in CCA, as well as elucidated its underlying mechanism. We first demonstrated that regorafenib not only inhibited growth but also induced...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Yeh, Chun-Nan, Chang, Yu-Chan, Su, Yeu, Shin-Shian Hsu, Dennis, Cheng, Chi-Tung, Wu, Ren-Chin, Chung, Yi-Hsiu, Chiang, Kun-Chun, Yeh, Ta-Sen, Lu, Meng-Lun, Liu, Chun-Yu, Mu-Hsin Chang, Peter, Chen, Ming-Han, Huang, Chi-Ying F., Hsiao, Michael, Chen, Ming-Huang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768338/
https://ncbi.nlm.nih.gov/pubmed/29371921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23049
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