Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma

Cholangiocarcinoma (CCA) is characterized by a uniquely aggressive behavior and lack of effective targeted therapies. After analyzing the gene expression profiles of seven paired intrahepatic CCA microarrays, a novel sphingosine kinase 1 (SPHK1)/sphingosine-1-phosphate (S1P) pathway and a novel targ...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Ming-Huang, Yen, Chueh-Chuan, Cheng, Chi-Tung, Wu, Ren-Chin, Huang, Shih-Chiang, Yu, Chung-Shan, Chung, Yi-Hsiu, Liu, Chun-Yu, Chang, Peter Mu-Hsin, Chao, Yee, Chen, Ming-Han, Chen, Yu-Fen, Chiang, Kun-Chun, Yeh, Ta-Sen, Chen, Tzu Chi, Huang, Chi-Ying F., Yeh, Chun-Nan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695139/
https://ncbi.nlm.nih.gov/pubmed/26090720
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