Antitumor activity of the combination of an HSP90 inhibitor and a PI3K/mTOR dual inhibitor against cholangiocarcinoma

The PI3K/Akt/mTOR pathway is overactivated and heat shock protein (HSP) 90 is overexpressed in common cancers. We hypothesized that targeting both pathways can kill intrahepatic cholangiocarcinoma (CCA) cells. HSP90 and PTEN protein expression was evaluated by immunohistochemical staining of samples...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chen, Ming-Huang, Chiang, Kun-Chun, Cheng, Chi-Tung, Huang, Shih-Chiang, Chen, Yeng-Yang, Chen, Tsung-Wen, Yeh, Ta-Sen, Jan, Yi-Yin, Wang, Hsi-Ming, Weng, Jiang-Jie, Chang, Peter Mu-Hsin, Liu, Chun-Yu, Li, Chung-Pin, Chao, Yee, Chen, Ming-Han, Huang, Chi-Ying F., Yeh, Chun-Nan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058012/
https://ncbi.nlm.nih.gov/pubmed/24796583
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados