Identification of MALT1 as both a prognostic factor and a potential therapeutic target of regorafenib in cholangiocarcinoma patients

Intrahepatic cholangiocarcinoma (CCA) is an aggressive cancer that lacks an effective targeted therapy. Here, we assessed the therapeutic efficacy of regorafenib in CCA, as well as elucidated its underlying mechanism. We first demonstrated that regorafenib not only inhibited growth but also induced...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yeh, Chun-Nan, Chang, Yu-Chan, Su, Yeu, Shin-Shian Hsu, Dennis, Cheng, Chi-Tung, Wu, Ren-Chin, Chung, Yi-Hsiu, Chiang, Kun-Chun, Yeh, Ta-Sen, Lu, Meng-Lun, Liu, Chun-Yu, Mu-Hsin Chang, Peter, Chen, Ming-Han, Huang, Chi-Ying F., Hsiao, Michael, Chen, Ming-Huang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768338/
https://ncbi.nlm.nih.gov/pubmed/29371921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23049
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