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Extracellular acidification induces ROS- and mPTP-mediated death in HEK293 cells
The extracellular pH (pHe) is a key determinant of the cellular (micro)environment and needs to be maintained within strict boundaries to allow normal cell function. Here we used HEK293 cells to study the effects of pHe acidification (24 h), induced by mitochondrial inhibitors (rotenone, antimycin A...
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| Publicado no: | Redox Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5767902/ https://ncbi.nlm.nih.gov/pubmed/29331741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.12.018 |
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