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Is mPTP the gatekeeper for necrosis, apoptosis, or both?
Permeabilization of the mitochondrial membranes is a crucial step in apoptosis and necrosis. This phenomenon allows the release of mitochondrial death factors which trigger or facilitate different signaling cascades ultimately causing the execution of the cell. The mitochondrial permeability transit...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3050112/ https://ncbi.nlm.nih.gov/pubmed/20888866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2010.09.013 |
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