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Is mPTP the gatekeeper for necrosis, apoptosis, or both?

Permeabilization of the mitochondrial membranes is a crucial step in apoptosis and necrosis. This phenomenon allows the release of mitochondrial death factors which trigger or facilitate different signaling cascades ultimately causing the execution of the cell. The mitochondrial permeability transit...

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Bibliografiska uppgifter
Huvudupphovsmän: Kinnally, Kathleen W., Peixoto, Pablo M., Ryu, Shin-Young, Dejean, Laurent M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050112/
https://ncbi.nlm.nih.gov/pubmed/20888866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2010.09.013
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