Synthesis and SAR of 1,2,3,4-Tetrahydroisoquinoline-Based CXCR4 Antagonists

[Image: see text] CXCR4 is the most common chemokine receptor expressed on the surface of many cancer cell types. In comparison to normal cells, cancer cells overexpress CXCR4, which correlates with cancer cell metastasis, angiogenesis, and tumor growth. CXCR4 antagonists can potentially diminish th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Wilson, Robert J., Jecs, Edgars, Miller, Eric J., Nguyen, Huy H., Tahirovic, Yesim A., Truax, Valarie M., Kim, Michelle B., Kuo, Katie M., Wang, Tao, Sum, Chi Shing, Cvijic, Mary E., Paiva, Anthony A., Schroeder, Gretchen M., Wilson, Lawrence J., Liotta, Dennis C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767887/
https://ncbi.nlm.nih.gov/pubmed/29348805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00381
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados