Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis

The mevalonate pathway produces isopentenyl diphosphate (IPP), a building block for polyisoprenoid synthesis, and is a crucial pathway for growth of the human bacterial pathogen Enterococcus faecalis. The final enzyme in this pathway, mevalonate diphosphate decarboxylase (MDD), acts on mevalonate di...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Chen, Chun-Liang, Mermoud, James C., Paul, Lake N., Steussy, Calvin Nicklaus, Stauffacher, Cynthia V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2017
Ämnen:
Protein Structure and Folding
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766736/
https://ncbi.nlm.nih.gov/pubmed/29025876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.802223
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