Inhibition of Bacterial Mevalonate Diphosphate Decarboxylase by Eriochrome Compounds

Mevalonate diphosphate decarboxylase (MDD; EC 4.1.1.33) catalyzes the irreversible decarboxylation of mevalonate diphosphate in the mevalonate pathway to form isopentenyl diphosphate, which is a precursor in the biosynthesis of many essential polyisoprenoid natural products, including sterols. In lo...

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Detalhes bibliográficos
Publicado no:Arch Biochem Biophys
Main Authors: Skaff, D. Andrew, McWhorter, William J., Geisbrecht, Brian V., Wyckoff, Gerald J., Miziorko, Henry M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456016/
https://ncbi.nlm.nih.gov/pubmed/25499551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2014.12.002
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