Paracrine and epigenetic control of CAF-induced metastasis: the role of HOTAIR stimulated by TGF-ß1 secretion

BACKGROUND: The communication between carcinoma associated fibroblasts (CAFs) and cancer cells facilitate tumor metastasis. In this study, we further underlying the epigenetic mechanisms of CAFs feed the cancer cells and the molecular mediators involved in these processes. METHODS: MCF-7 and MDA-MB-...

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Bibliografiske detaljer
Udgivet i:Mol Cancer
Main Authors: Ren, Yu, Jia, Huan-huan, Xu, Yi-qi, Zhou, Xuan, Zhao, Xiao-hui, Wang, Yun-fei, Song, Xin, Zhu, Zhi-yan, Sun, Ting, Dou, Yan, Tian, Wei-ping, Zhao, Xiu-lan, Kang, Chun-sheng, Mei, Mei
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765658/
https://ncbi.nlm.nih.gov/pubmed/29325547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0758-4
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