Paracrine and epigenetic control of CAF-induced metastasis: the role of HOTAIR stimulated by TGF-ß1 secretion

BACKGROUND: The communication between carcinoma associated fibroblasts (CAFs) and cancer cells facilitate tumor metastasis. In this study, we further underlying the epigenetic mechanisms of CAFs feed the cancer cells and the molecular mediators involved in these processes. METHODS: MCF-7 and MDA-MB-...

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Bibliographic Details
Published in:Mol Cancer
Main Authors: Ren, Yu, Jia, Huan-huan, Xu, Yi-qi, Zhou, Xuan, Zhao, Xiao-hui, Wang, Yun-fei, Song, Xin, Zhu, Zhi-yan, Sun, Ting, Dou, Yan, Tian, Wei-ping, Zhao, Xiu-lan, Kang, Chun-sheng, Mei, Mei
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765658/
https://ncbi.nlm.nih.gov/pubmed/29325547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0758-4
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