TGF-β1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma

TGF-β1, a potent EMT (epithelial-mesenchymal transition) inducer present in the tumor microenvironment, is involved in the metastasis and progression of various carcinomas, including esophageal squamous cell carcinoma (ESCC). TIP30 (30kDa HIV-1 Tat interacting protein) is a putative tumor metastasis...

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Publicado en:Oncotarget
Autores principales: Bu, Fangfang, Liu, Xing, Li, Jingjing, Chen, Shukun, Tong, Xin, Ma, Chunsheng, Mao, Hui, Pan, Fei, Li, Xiaoyan, Chen, Bo, Xu, Liyan, Li, Enmin, Kou, Geng, Han, Jun, Guo, Shangjing, Zhao, Jian, Guo, Yajun
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385840/
https://ncbi.nlm.nih.gov/pubmed/25544767
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